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The first vaccine targeted which disease smallpox

By Dana Jordan
Published in Trivia
February 02, 2024
2 min read
The first vaccine targeted which disease smallpox

The First Vaccine Targeted Which Disease? Smallpox.

Smallpox, a highly contagious and deadly disease, plagued humanity for centuries. But thanks to the development of vaccines, smallpox became the first disease to be successfully targeted and eradicated through vaccination. This significant accomplishment in the field of medicine has saved countless lives and shaped the course of public health strategies worldwide.

A Brief History of Smallpox

Smallpox is caused by the variola virus and was responsible for devastating epidemics throughout history. It is believed to have first emerged thousands of years ago in ancient Egypt or India. The disease quickly spread across continents, leaving behind scars of suffering and death.

Smallpox was particularly notorious for its high mortality rate, estimated to range from 20% to 60% in cases of severe infection. Survivors were often left disfigured or blinded. The disease spread through respiratory droplets, making it highly contagious and difficult to contain.

The Discovery of Vaccination

The first steps towards conquering smallpox were taken in the late 18th century by an English physician and scientist named Edward Jenner. He noticed that milkmaids who contracted a mild illness called cowpox seemed to be immune to smallpox.

Jenner hypothesized that exposure to cowpox could protect individuals from the more severe smallpox virus. In 1796, he conducted a groundbreaking experiment. Jenner collected fluid from a cowpox sore and inoculated an eight-year-old boy with it. Weeks later, he exposed the boy to smallpox but observed that he remained healthy.

This experiment laid the foundation for vaccination, derived from the Latin word “vacca” meaning cow. The discovery of vaccination as a preventive measure against smallpox was a breakthrough moment in medical history.

The Smallpox Vaccine and Eradication

Building upon Jenner’s work, scientists and researchers worldwide dedicated themselves to combating smallpox through vaccination. The smallpox vaccine involved using a similar but less harmful virus known as vaccinia, which provokes a protective immune response without causing the severe symptoms of smallpox.

Mass vaccination campaigns were launched, and international cooperation aimed at eradicating the disease gained momentum. The World Health Organization (WHO) orchestrated a global smallpox eradication campaign starting in 1967.

After years of intense efforts and collaboration, the world witnessed a historic moment in 1977. Ali Maow Maalin, a hospital cook in Somalia, became the last person to contract naturally occurring smallpox. The disease was effectively eradicated through vaccinations, marking one of the greatest achievements in the history of medicine.

The Legacy of Smallpox Vaccination

The eradication of smallpox not only eliminated a devastating disease but also showcased the power of vaccination as a public health tool. It inspired subsequent vaccination efforts against other infectious diseases and highlighted the importance of global cooperation in controlling epidemics.

Today, vaccination remains an essential strategy in preventing a wide range of diseases. Smallpox vaccination became a shining example of how humankind can overcome immense health challenges through scientific advancements and collaborative efforts.

Smallpox

Edward Jenner

Image Sources:

  1. Smallpox - eRepublic
  2. Edward Jenner - BBC

Sources:


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Dana Jordan

Dana Jordan

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